膜科学与技术

杂萘联苯共聚醚砜血液透析膜的制备与性能

作者：徐象贤¹，张守海¹，刘乾¹，王昭琪¹，刘炳荣²，蹇锡高¹

单位： 1．大连理工大学化工学院，辽宁省高性能树脂工程技术研究中心，辽宁省高分子科学与工程重点实验室，大连 116024；２．江西三鑫医疗科技股份有限公司，南昌330200

关键词：杂萘联苯共聚醚砜；中空纤维膜；血液透析；制备

出版年,卷(期):页码： 2020,40(5):1-8

摘要：

以不同结构的杂萘联苯共聚醚砜（PPBES）为膜材料，通过相转化法制备了一系列中空纤维血液透析膜。结合旋转黏度仪、接触角测量仪、扫描电子显微镜等，分析了PPBES结构对纺丝液的热力学稳定性、纺丝液旋转黏度、中空纤维血液透析膜结构及性能的影响。实验结果表明，随着PPBES中二氮杂萘酮结构单元含量的增加，纺丝液热力学稳定性降低，纺丝液黏度增大，膜的亲水性得到改善。血液透析膜对牛血清蛋白（BSA）的截留率均大于93%，纯水通量均大于23.9 L/(m2·h)，其中PPBES6040血液透析膜的纯水通量和BSA通量分别为34.5 L/(m2·h)和25.5 L/(m2·h)，通量恢复率为68.4%。中空纤维膜拉伸强度均大于6 MPa。

A series of hollow fiber hemodialysis membranes were prepared by phase inversion using copoly (phthalazinone biphenyl ether sulfone) (PPBES) with different content of phthalazinone moieties. The effects of PPBES structure on the thermodynamic stability of spinning solution, spinning solution viscosity, membrane structure and performance were investigated by rotational viscometer, contact angle measuring instrument and scanning electron microscope. The results show that thermodynamic stability of the spinning solution decreased with the increase of the content of phthalazinone moieties, while the viscosity of the spinning solution increased and the hydrophilicity of the membrane improved. The rejection against bovine serum albumin (BSA) for hollow fiber membranes was more than 93%, and the pure water flux was higher than 23.9 L/m2h. The pure water flux and BSA flux of the PPBES6040 membrane were 34.5 L/m2h and 25.5 L/m2h, respectively, and the flux recovery rate (FRR) was 68.4%. The tensile strength of hollow fiber membranes were no less than 6 MPa.

徐象贤(1995-)，男，辽宁大连人，硕士研究生，研究方向为中空纤维血液透析膜，E-mail: xuxiangxian@mail.dlut.edu.cn

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