膜科学与技术

纳滤对低聚壳聚糖制备液的纯化研究

作者：
韩永萍林强

单位：纳滤膜；纯化；低聚壳聚糖

关键词： TQ028.8

出版年,卷(期):页码： 2012,32(4):75-80

摘要：

对低聚壳聚糖制备液进行了纳滤纯化研究。试验确定纳滤的最佳操作条件为35~40℃、操作压力为1.0Mpa，制备液在纳滤之前还应稀释2.5倍，间歇恒容渗滤过程的每一运行周期的最优浓缩倍数为1.5倍。在该条件运行下，制备液中的单糖和大部分二糖及一价盐离子被脱出，高活性低聚壳聚糖的纯度高达92%，料液体积被浓缩了接近2倍。

In this paper, the experimental research was made for the desalination and purification Chiitooligosaccharides (COS) solution with nano-filtration (NF). The optimal operation conditions of NF purified COS solution were obtained as follow: 35~40℃, 1.0MPa operation pressure, COS solution diluted 2.5 times to be the feed solution of NF, and the optimal solution volume concentration factor of a period of the batch constant volume diafiltration process was 1.5. Under this conditions, the monosaccharide and most of disaccharide and monovalent salts were removed from COS solution by NF, and the purity of high biological activity COS was up to 92%, at the same time the volume was condensed to half of the initial feed solution.

韩永萍(1971- ), 女, 山东人, 副教授, 博士. E-mail:hypyyt @163.com

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