膜科学与技术

金属-有机骨架材料[Zn2Camph2(dabco)]·DMF·H2O作为手性选择剂的高分子膜及其应用研究

作者：艾萍，张紫恒，袁黎明＊

单位：（云南师范大学化学化工学院，昆明市 650500）

关键词： D,L-对羟基苯甘氨酸；金属-有机骨架材料[Zn2Camph2(dabco)]·DMF·H2O；MOFs-醋酸纤维素混合膜；手性分离膜；手性分离

出版年,卷(期):页码： 2018,38(5):84-87

摘要：

以醋酸纤维素为基质膜，以手性金属-有机骨架材料[Zn2Camph2(dabco)]·DMF·H2O作为手性识别剂制备醋酸纤维素混合膜，对D,L-对羟基苯甘氨酸进行了分离研究。该文详细研究了操作压力、操作时间以及D,L-对羟基苯甘氨酸浓度对膜渗析性能的影响。在优选分离条件下，当D,L-对羟基苯甘氨酸浓度为0.3mg/mL时，该膜对D,L-对羟基苯甘氨酸分离的对映体过剩值（e.e.）为42.4%，其对D,L-对羟基苯甘氨酸对映体有一定的拆分效果。

A enantioselective membrane was prepared by mixed [Zn2Camph2(dabco)]·DMF·H2O and cellulose acetate. The enantioseparation parameters of the mixed membrane for D,L-p-hydroxyphenylglycine was optimized by operating pressure, dialysis time, feed concentration of D,L-p-hydroxyphenylglycine, etc. When the feed concentrateion of D,L-p-hydroxyphenylglycine was 0.3mg/mL, over 42.4% of enantiomeric excess(e.e.) could be obtained by dialysis. The results showed that the MOFs-cellulose acetate mixed membrane can separate the optical isomers of D,L-p-hydroxyphenylglycine.

第一作者简介：艾萍（1962-），女，四川高县人，教授，从事手性分离研究，E-mail：aipdeyx@aliyun.com 通讯作者：袁黎明(1961-), 男, 重庆人, 教授, 从事手性分离研究, E-mail：yuan_limingpd@126.com

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