Position:Home >> Abstract

Application of ceramic ultrafiltration membranes for dextran separation
Authors: ZHANG Yun, QI Ting, CHEN Xianfu, QIU Minghui, FAN Yiqun
Units: (State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing 210009, China
KeyWords: ultrafiltration, ceramic membrane, dextran, separation
ClassificationCode:TQ028.8
year,volume(issue):pagination: 2018,38(2):86-91

Abstract:
 In this work, ZrO2 ultrafiltration membrane (MWCO=2700 Da) was used to separate and purify the dextran solution. The influences of operating pressure, temperature, crossflow velocity and feed concentration on membrane flux and retention rate as well as the stability were investigated. It’s demonstrated that the membrane flux and retention rate of dextran increased with transmembrane pressure. When the transmembrane pressure was 0.3 MPa, the separation factor of dextran and fructose reached the maximum. With the increase of temperature, the membrane flux increased but the retention rate of dextran fell down. With the increase of crossflow velocity, the membrane flux also increased. When crossflow velocity was 2.8 m/s, retention rates of dextran achieved up to 92%. When the feed concentration was 60 g/L, the separation performance of ceramic membrane was almost stable in a 12 h operating test. The flux and separation factor were stable at 24 L·m-2·h-1 and 11.5, respectively. The results indicated that the ZrO2 ultrafiltration membrane exhibited a good potential application in the separation and purification of dextran.

Funds:
国家自然科学基金项目(91534108,21506093,21706115);国家高技术研究发展计划项目(2012AA03A606);江苏高校优势学科建设工程(PAPD);江苏省“六大人才高峰”项目(2012JNHB016)。

AuthorIntro:
第一作者简介: 张云(1993-), 女, 江苏省句容市人, 硕士, 从事膜分离材料的研究与应用. *通讯联系人

Reference:
  [1] 陈山, 郭祀远, 杨晓泉. 采用分级超滤法精制右旋糖酐[J]. 食品与发酵工业, 2004(06):42-45.
 [2] 刘丽娅. 溶析结晶辅助膜分离技术纯化药用右旋糖酐的研究[D]. 广西大学, 2008.
 [3] 常国炜, 梁达奉, 张九花, 等. 发酵耦合酶解高效制备右旋糖酐工艺研究[J]. 广西科学, 2014(06):619-623.
 [4] 章朝晖. 右旋糖酐的制备及应用[J]. 四川化工与腐蚀控制, 2001(01):50-52.
 [5] Chen S, Liu L, Lu J, et al. Clinical dextran purified by electric ultrafiltration coupling with solvent crystallization[J]. Comptes Rendus Chime, 2008,11(1-2):80-83.
 [6] Hua Y D. Preparation of Dextran by Membrane Separation[J]. Chinese Journal of Pharmaceuticals, 2008,39(10):661-738.
 [7] 许丹枫. 超滤技术代替乙醇沉淀粗右旋糖酐工艺研究[J]. 天津科技, 1997(05):36.
 [8] 郭振友, 许丹枫, 吴明. 超滤技术代替乙醇沉淀粗右旋糖酐工艺研究[J]. 中国纺织大学学报, 2000(02):100-103.
 [9] Wei X F. Discussing New Process of Dextran Production[J]. Enterprise Science & Technology & Development, 2012.
[10] Guo S Y, Xiao K J, Chen S, et al. Separation and purification of medicinal dextran using membrane filtration/crystallization[J]. VDI-Berichte, 2005(1901):903-908.
[11] Vinther F, Pinelo M, Brøns M, et al. Mathematical modelling of dextran filtration through hollow fibre membranes[J]. Separation & Purification Technology, 2014,125(14):21-36.
[12] Chen S. Multi-stage Ultrafiltration Separation of Dextran[J]. Food & Fermentation Industries, 2004.
[13] 邓建平, 杨万泰. 表面光接枝技术及其在分离膜中的应用[J]. 膜科学与技术, 1999(3):13-18.
[14] 花逾冬, 曾和. 膜分离法制备右旋糖酐[J]. 中国医药工业杂志, 2008(10):738-740.
[15] Pu Y, Zou Q, Liu L, et al. Clinical dextran purified by fractional ultrafiltration coupled with water washing[J]. Carbohydrate Polymers, 2012,87(2):1257-1260.
[16] 姜毅, 雷光鸿, 王元春, 等. 酶法耦合分级膜制备右旋糖酐的研究[J]. 食品科技, 2015(02):323-327.
[17] 闻娟娟, 范益群. 无缺陷氧化铝微滤膜的制备研究[J]. 膜科学与技术, 2013,33(5):19-24.
[18] 郭立玮, 金万勤. 无机陶瓷膜分离技术对中药药效物质基础研究的意义[J]. 膜科学与技术, 2002,22(4):46-49.
[19] 祝振洲, 苏仪, 伊守亮, 等. 响应曲面法优化优先透乙醇渗透汽化复合膜的操作条件[J]. 膜科学与技术, 2010(03):70-75.
[20] Puhlfurss P, Voigt A, Weber R, et al. Microporous TiO2 membranes with a cut off < 500 Da[J]. Journal of Membrane Science, 2000,174(1):123-133.
[21] 李梅, 高能文, 范益群. 疏水陶瓷膜脱除油中水分的研究[J]. 膜科学与技术, 2012,32(3):86-90.
[22] 王世清, 于丽娜, 杨庆利, 等. 超滤膜分离纯化花生壳中水溶性膳食纤维[J]. 农业工程学报, 2012(03):278-282.
[23] 汪维云, 施燕, 时宏斌, 等. 超滤膜分离灰树花多糖的工艺条件优化[J]. 食品与发酵工业, 2010(04):190-193.
[24] 张喜峰, 鲁丽文, 张丽娟, 等. 无机陶瓷膜分离沙枣多糖的研究[J]. 北京联合大学学报(自然科学版), 2014(03):33-37.
[25] 董艳. 膜分离提取纯化中药多糖的工艺研究[D]. 天津大学, 2007.
[26] 王博, 斯聪聪, 程国才. 响应面优化超滤膜分离灵芝多糖工艺[J]. 食品工业, 2015(12):1-4.

Service:
Download】【Collect

《膜科学与技术》编辑部 Address: Bluestar building, 19 east beisanhuan road, chaoyang district, Beijing; 100029 Postal code; Telephone:010-80492417/010-80485372; Fax:010-80485372 ; Email:mkxyjs@163.com

京公网安备11011302000819号